Crossword clue: a structure in a hollow organ (like the heart) with a flap to insure one-way flow of fluid through it
1 answer found in Letterora's clue database (Wikidata facts, Open Trivia DB, WordNet and Webster definitions — all licensed sources).
Possible answers
a structure in a hollow organ (like the heart) with a flap to insure one-way flow of fluid through it