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Crossword clue: action that makes a problem or a disease (or its symptoms) worse

2 answers found in Letterora's clue database (Wikidata facts, Open Trivia DB, WordNet and Webster definitions — all licensed sources).

Possible answers

aggravation 11 letters wn-def

action that makes a problem or a disease (or its symptoms) worse

exacerbation 12 letters wn-def

action that makes a problem or a disease (or its symptoms) worse

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