Crossword clue: any general reduction in vitality and strength of body and mind resulting from a debilitating chronic disease

The most common answer is cachexia (8 letters).

2 answers found in Letterora's clue database (Wikidata facts, Open Trivia DB, WordNet and Webster definitions — all licensed sources).

Possible answers

cachexia 8 letters wn-def

any general reduction in vitality and strength of body and mind resulting from a debilitating chronic disease

cachexy 7 letters wn-def

any general reduction in vitality and strength of body and mind resulting from a debilitating chronic disease