Crossword clue: lady; mistress; madam; -- a title of respect used in spain, prefixed to the christian name of a lady.

The most common answer is dona (4 letters).

2 answers found in Letterora's clue database (Wikidata facts, Open Trivia DB, WordNet and Webster definitions — all licensed sources).

Possible answers

dona 4 letters web-def

a Spanish courtesy title or form of address for a woman

donya 5 letters web-def

Lady; mistress; madam; -- a title of respect used in Spain, prefixed to the Christian name of a lady.