Crossword clue: that which annoys. piers plowman.
1 answer found in Letterora's clue database (Wikidata facts, Open Trivia DB, WordNet and Webster definitions — all licensed sources).
Possible answers
To annoy; to vex. [Obs. or Prov. Eng.] Piers Plowman. All that noyed his heavy spright. Spenser.